hrp0092fc4.5 | Fat Metabolism and Obesity Session | ESPE2019

Leptin Gene Methylation Status in Egyptian Infants

Omar Omneya Magdy , Naguib Massoud Mohamed , Elwafa Reham Abo , Gerges Mary

Background: Obesity results from interactions between environmental and genetic factors. Despite a relatively high heritability of common, non-syndromic obesity (40–70%), the search for genetic variants contributing to susceptibility has been a challenging task. To date, more than 40 genetic variants have been associated with obesity and fat distribution. However, since these variants do not fully explain the heritability of obesity, other forms of va...